- Molecular Biology
- Viral Vectors & Cell Engineering
- Protein Engineering & Production
- Antibody Discovery & Engineering
- Antibody Production
-
Analytics & Formulation
- Overview
- Purity Analysis by CE-SDS
- Aggregation Analysis
- Charge Variant Analysis
- De Novo Antibody Sequencing
- Intact Mass Analysis
- Sequence Confirmation by Mass Spectrometry
- N-terminal Sequencing
- Post-Translational Modification
- N-glycan Analysis
- Thermostability Analysis
- Stability Analysis
- Formulation Development
- Developability Analysis
- FAQs
- R&D and cGxP Bioassay Development
- Protein Chemistry
- Development & Manufacturing in LakePharma Hayward, CA
- Development & Manufacturing in LakePharma Hopkinton, MA
- Consulting Services
De Novo Antibody Sequencing
LakePharma has developed proprietary methods to perform de novo antibody sequencing, a technique by which the amino acid sequence of an antibody is discovered without prior knowledge of the DNA or protein sequence. This differs from sequence confirmation by peptide mapping, a service where the protein sequence is already known and is used as a guideline to confirm the sequence. De novo antibody sequencing is a valuable tool for enabling recombinant production of a commercial antibody with useful properties, and is frequently faster than raising new antibodies from immunized sources.
Key benefits:
Discover antibody’s sequence without prior knowledge
100% sequence coverage and more than 95% working sequence
Produce antibody performs as well as or even better than the original one
Download our Proteomic Sequencing and Resurrection of a Monoclonal Antibody presentation by clicking here.
| Catalog # | Name | Timeline | Price |
|---|---|---|---|
| 65050 | De Novo Antibody Sequencing I | 1 month | Request |
| 65100 | De Novo Antibody Sequencing II | 3 months | Request |
